Integrated two-liquid phase bioconversion and product-recovery processes for the oxidation of alkanes: Process design and economic evaluation

Author(s):  
Renata G. Mathys ◽  
Andrew Schmid ◽  
Bernard Witholt
Author(s):  
Guus H C Dubbink ◽  
Thomas R J Geverink ◽  
Bas Haar ◽  
Harald W Koets ◽  
Abhay Kumar ◽  
...  

Author(s):  
Joseph Ddumba Lwanyaga ◽  
Hillary Kasedde ◽  
John Baptist Kirabira ◽  
Alan Shemi ◽  
Sehliselo Ndlovu

Molecules ◽  
2019 ◽  
Vol 24 (18) ◽  
pp. 3356 ◽  
Author(s):  
Francisco Aguilar ◽  
Thomas Scheper ◽  
Sascha Beutel

The sesquiterpene (+)-zizaene is the direct precursor of khusimol, the main fragrant compound of the vetiver essential oil from Chrysopogon zizanioides and used in nearly 20% of men’s fine perfumery. The biotechnological production of such fragrant sesquiterpenes is a promising alternative towards sustainability; nevertheless, product recovery from fermentation is one of the main constraints. In an effort to improve the (+)-zizaene recovery from a metabolically-engineered Escherichia coli, we developed an integrated bioprocess by coupling fermentation and (+)-zizaene recovery using adsorber extractants. Initially, (+)-zizaene volatilization was confirmed from cultivations with no extractants but application of liquid–liquid phase partitioning cultivation (LLPPC) improved (+)-zizaene recovery nearly 4-fold. Furthermore, solid–liquid phase partitioning cultivation (SLPPC) was evaluated by screening polymeric adsorbers, where Diaion HP20 reached the highest recovery. Bioprocess was scaled up to 2 L bioreactors and in situ recovery configurations integrated to fermentation were evaluated. External recovery configuration was performed with an expanded bed adsorption column and improved (+)-zizaene titers 2.5-fold higher than LLPPC. Moreover, internal recovery configuration (IRC) further enhanced the (+)-zizaene titers 2.2-fold, whereas adsorption velocity was determined as critical parameter for recovery efficiency. Consequently, IRC improved the (+)-zizaene titer 8.4-fold and productivity 3-fold from our last report, achieving a (+)-zizaene titer of 211.13 mg L−1 and productivity of 3.2 mg L−1 h−1. This study provides further knowledge for integration of terpene bioprocesses by in situ product recovery, which could be applied for many terpene studies towards the industrialization of fragrant molecules.


2015 ◽  
Vol 66 (3) ◽  
pp. 296-306 ◽  
Author(s):  
Sheng-Lun Lin ◽  
Kuo-Lin Huang ◽  
I-Ching Wang ◽  
I-Cheng Chou ◽  
Yi-Ming Kuo ◽  
...  

Author(s):  
Serdar Tumkor ◽  
John W. Sutherland ◽  
Vishesh V. Kumar

Discarded electrical and electronic equipment contains valuable materials, low value parts, and hazardous substances. There is a growing concern regarding the management of end-of-use equipment owing to the environmental concerns associated with discarding used devices. Electronic waste or scrap consumes valuable landfill space and may ultimately contaminate groundwater sources. In addition, replacing discarded components with new components typically consumes valuable virgin material resources. With the advent of the WEEE (Waste Electrical and Electronic Equipment) Directive, used electrical and electronic products are now being recovered in Turkey as a European Union (EU) candidate country, and several companies in Turkey have begun to recover latent value through disassembly and reuse/recycling of materials and components. To remain competitive, these companies must implement economical and environmentally responsible recovery processes. There are a number of research challenges associated with product recovery. This paper describes the current product recovery infrastructure in Turkey, and discusses future trends and drivers for successful product take-back.


2019 ◽  
Vol 44 (47) ◽  
pp. 25524-25541 ◽  
Author(s):  
V.R. Paida ◽  
S.R.A. Kersten ◽  
A.G.J. van der Ham ◽  
D.W.F. Brilman

1987 ◽  
Vol 3 (3) ◽  
pp. 131-140 ◽  
Author(s):  
Steven Roffler ◽  
Harvey W. Blanch ◽  
Charles R. Wilke

1972 ◽  
Vol 12 (02) ◽  
pp. 143-155 ◽  
Author(s):  
E.L. Claridge

Abstract A new correlation bas been developed for estimating oil recovery in unstable miscible five-spot pattern floods. It combines existing methods of predicting areal coverage and linear displacement efficiency and was used to calculate oil recovery for a series of assumed slug sizes in a live-spot CO2 slug-waterflood pilot test. The economic optimum slug size varies with CO2 cost; at anticipated CO2 costs the pilot would generate an attractive profit if performance is as predicted Introduction Selection of good field prospects for application of oil recovery processes other than waterflooding is often difficult. The principal reason is that other proposed displacing agents are far more costly proposed displacing agents are far more costly than water and usually sweep a lesser fraction of the volume of an oil reservoir (while displacing oil more efficiently from this fraction). Such agents must be used in limited amounts as compared with water; and this amount must achieve an appreciable additional oil recovery above waterflooding recovery. For these reasons, there is in general much less economic margin for engineering error in processes other than waterflooding. The general characteristics of the various types of supplemental recovery processes are well known, and adequate choices can be made of processes to be considered in more detail with respect to a given field. Comparative estimates must then be made of process performance and costs in order to narrow the choice. A much more detailed, definitive process-and-economic evaluation is eventually process-and-economic evaluation is eventually required of the chosen process before an executive decision can be made to commit large amounts of money to such projects. It is in the area between first choice and final engineering evaluation that this work applies. A areal cusping and vertical coning into producing wells. These effects can be seated by existing "desk-drawer" correlation which can confirm or deny the engineer's surmise that he has an appropriate match of recovery process and oil reservoir characteristics is of considerable value in determining when to undertake the costly and often manpower-consuming task of a definitive process-and-economic evaluation. process-and-economic evaluation. An examination of the nature of the developed crude oil resources in the U.S. indicates that the majority of the crude oil being produced is above 35 degrees API gravity and exists in reservoirs deeper than 4,000 ft. The combination of hydrostatic pressure on these oil reservoirs, the natural gas usually present in the crude oil in proportion to this pressure, the reservoir temperatures typically found, and the distribution of molecular sizes and types in the crude oil corresponding to the API gravity results in the fact that, in the majority of cases, the in-place crude oil viscosity was originally no more than twice that of water. A large proportion of these oil reservoirs have undergone pressure decline, gas evolution and consequent increase in crude oil viscosity. However, an appreciable proportion are still at such a pressure and proportion are still at such a pressure and temperature that miscibility can be readily attained with miscible drive agents such as propane or carbon dioxide, and the viscosity of the crude oil is such that the mobility of these miscible drive agents is no more than 50 time s that of the crude oil. Under these circumstances, a possible candidate situation for the miscible-drive type of process may exist. process may exist. Supposing that such a situation is under consideration, the next question is: what specific miscible drive process, and how should it be designed to operate? In some cases, the answer is clear: when the reservoir has a high degree of vertical communication (high permeability and continuity of the permeable, oil-bearing pore space in the vertical direction), then a gravity-stabilized miscible flood is the preferred mode of operation; and the particular drive agent or agents can be chosen on the basis of miscibility requirements, availability and cost. SPEJ P. 143


2013 ◽  
Vol 46 (11) ◽  
pp. 759-769 ◽  
Author(s):  
Sekwang Yoon ◽  
Hyun Jun Cho ◽  
Yeong-Koo Yeo ◽  
Jin-Kuk Kim

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